Fmoc-L-glutamic acid γ-methyl ester

Fmoc-L-glutamic acid γ-methyl ester - Names and Identifiers

Name	Fmoc-L-Glutamic acid gamma-methyl ester
Synonyms	Fmoc-Glu-OMe Fmoc-Glu(Ome)-Oh FMOC-GLU(OME)-OH Fmoc-Glu(OMe)-OH FMOC-L-GLU(ME)-OH Fmoc-L-Glu(Me)-Oh Fmoc-L-glutamic acid γ-methyl ester Fmoc-L-Glutamic Acid Γ-Methyl Ester Fmoc-L-Glutamic acid gamma-methyl ester FMOC-L-GLUTAMIC ACID-GAMMA-METHYL ESTER Fmoc-L-Glutamic Acid-Gamma-Methyl Ester N-alpha-Fmoc-L-glutamicacidgamma-methylester N-Alpha-Fmoc-L-Glutamicacidgamma-Methylester N-(9-Fluorenylmethyloxycarbonyl)-L-glutamic acid gamma-methyl ester N-(9-Fluorenylmethyloxycarbonyl)-L-Glutamic Acid Gamma-Methyl Ester N-Alpha-(9-Fluorenylmethoxycarbonyl)-L-Glutamic Acid Gamma-Methyl Ester N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-GLUTAMIC ACID GAMMA-METHYL ESTER N-Alpha-(9-Fluorenylmethyloxycarbonyl)-L-Glutamic Acid Gamma-Methyl Ester N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-GLUTAMIC ACID GAMMA-METHYL ESTER
CAS	145038-50-2

Fmoc-L-glutamic acid γ-methyl ester - Physico-chemical Properties

Molecular Formula	C21H21NO6
Molar Mass	383.39
Density	1.296±0.06 g/cm3(Predicted)
Boling Point	625.3±55.0 °C(Predicted)
Appearance	Powder
Color	White
pKa	3.70±0.10(Predicted)
Storage Condition	Sealed in dry,2-8°C
Physical and Chemical Properties	Storage Conditions: Store at 0-5 ℃

Fmoc-L-glutamic acid γ-methyl ester - Introduction

Fmoc-L-Glutamic acid gamma-methyl ester is an organic compound with the following properties:

1. Appearance: Fmoc-L-Glutamic acid gamma-methyl ester is a white crystalline solid.
2. Stability: This compound is relatively stable at room temperature.
3. Solubility: Fmoc-L-Glutamic acid gamma-methyl ester is soluble in some organic solvents (such as dimethyl sulfoxide, dichloromethane, etc.).

The main purpose of Fmoc-L-Glutamic acid gamma-methyl ester is to be used as a protecting group in the synthesis of peptides to control the reactivity of amino acids. It can be synthesized:

1. First, dissolve L-glutamic acid in sodium carbonate solution, and then add Fmoc-Cl. After the reaction proceeds, Fmoc-L-glutamic acid can be obtained.
2. Next, methanol and benzylidene chloride were added to the sodium carbonate solution. After the reaction, the Fmoc-L-Glutamic acid gamma-methyl ester can be obtained.

When using the Fmoc-L-Glutamic acid gamma-methyl ester, you need to pay attention to safety precautions:

1. This compound may be irritating to the eyes, skin and respiratory system, so protective measures should be taken when exposed, such as wearing protective glasses, gloves and masks.
2. Avoid inhaling dust or vapor from the solution, as respiratory irritation and discomfort may occur.
3. In use and storage, should be away from the fire and combustible.
4. Waste disposal should comply with local regulations to ensure safety.

Last Update：2024-04-09 21:21:28